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Accupril prescribing information

 



Full prescription information or package insert for Accupril

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Accupril description

Accupril is a drug used in the treatment of cardiovascular conditions. Accupril can also be used as a remedy in case of heart failure or hypertension as well as to prevent kidney failure caused by hypertension and diabetes. Accupril has a number of known side effects therefore before taking this drug, it is important that you are aware of all the necessary prescription information and dosage instructions in order to prevent overdose and consequent after-effects. Please note that the information below refers to accupril only and does not refer to any other drug. It is intended for patients taking Accupril and should be read carefully. However the details contained here is by no means exhaustive and is not recommended as a substitute for expert medical advice. The safety and effectiveness of Accupril in children is yet to be known therefore most of the information below refers to adults.

About the drug

When the blood pressure goes higher than the minimal blood pressure required to pump blood around your body, your organs and vessels are at risk of being damaged. The body increases blood pressure by narrowing your vessels and retaining waste water. This action is triggered by the release of a substance called angiotensin I which remains inactive until it is converted to angiotestin II by angiotestin-converting enzymes. Accupril lowers blood pressure by blocking the ACEs, hence preventing the action of angiotestin. It is important to note that high blood pressure declines gradually therefore for Accupril to be effective, it must be taken regularly. Furthermore, Accupril keeps the blood pressure under control, however it does not treat the underlying condition therefore you should continue with daily dose even after blood pressure has dropped to a sustained normal level.

How to take ACCUPRIL

Accupril can be taken with or without meal; alone or in combination with a thiazide diuretic. Using accupril with a thiazide diuretic could increase the blood pressure lowering effect compared to using either pill alone. Alcohol may increase the effect of Accupril, and could cause dizziness or fainting. Therefore avoid alcoholic beverages until you have your doctor’s approval. Take Accupril exactly as prescribed, and see your doctor regularly to ensure the drug is working properly without unwanted side effects. Do not discontinue taking this drug without first consulting your doctor. Do not take more than one tablet a day; should you miss a dose, take as soon as you possible but if too close to your next dose simply skip and then resume daily dose. The recommended dosage is as follows: High blood pressure: Initial dose of 10 or 20 mg taken once daily. A lower starting dose may be recommended for those with kidney problems or taking a diuretic. For adults over the age of 65, a starting dose of 10 mg is usually prescribed. Your doctor may increase your dose up to a total of 80 milligrams a day taken once a day or divided into two doses but this depends on the changes in your blood pressure over time. Congestive heart failure: Usual starting dose of 5 mg taken twice daily. Your doctor may increase the dose from week to week, up to as much as 20 to 40 milligrams daily, split into 2 equal doses. The dosage is lower for people with kidney problems.

Accupril must ONLY be taken under prescription from the doctor do not take this drug otherwise.

Overdose

Any medication taken in excess can have serious consequences. Although there is no specific information on the symptoms of overdose of accupril in humans, severe hypotension is a likely outcome. If you suspect an overdose, seek medical attention immediately.

Contraindications

Patients who are hypersensitive to this product and patients with a history of angioedema related to previous treatment with an ACE inhibitor are advised against taking Accupril.

Possible side effects

Dizziness and headache are the more common side effects, while less common ones include abdominal pain, coughing, fatigue, nausea and vomiting. Rare possible side effects include Angina (sever chest pain) back pain, bleeding in the stomach or intestines, bronchitis, changes in heart rhythm, constipation, depression, diarrhoea, dimmed vision, dizziness when first standing up, dry mouth or throat, extremely high blood pressure, fainting, fluid accumulation and swelling, gas, hair loss, heart attack, heart failure, hepatitis, high potassium, impotence, increased blood pressure, increased sweating, indigestion, inflammation of the pancreas, inflammation of the sinuses, insomnia, itching, kidney failure, joint pain, low blood pressure, muscle pain, nervousness, numbness/tingling, palpitations, rapid heartbeat, rash, sensitivity to light, severe allergic reactions, skin peeling, sleepiness, sore throat, stroke, swelling of the mouth and throat, urinary tract infection, vague feeling of illness and vertigo. Side effects cannot be anticipated. If any develops or worsens, inform your doctor as soon as possible who will then determine if it is safe for you to continue taking Accupril.

Special Warnings

Should you notice any swelling or difficulty swallowing or breathing, you should contact your doctor immediately as you may need emergency treatment. Notify your doctor of any light headedness and if you should faint discontinue daily dose and see your doctor.

Always inform medical staff that you are taking Accupril before undergoing surgery or anaesthesia. While using accupril, do not take any potassium supplements or salt substitutes containing potassium without consulting your doctor. Also if you notice any signs of liver damage such as yellow tinge to your skin and the whites of your eyes, or any signs of infection stop taking the drug and seek immediate medical; attention.

Drug Interactions

If taken alongside certain drugs, the effects of either drug could be increased, decreased, or altered. Drugs such as: Lithium (Eskalith, Lithobid); Magnesium; Tetracycline (Sumycin) Potassium-sparing diuretics such as Aldactone, Dyazide, Moduretic; Potassium supplements such as Slow-K and K-Dur; Salt substitutes containing potassium and Diuretics such as Lasix; are known to interact with accupril therefore do not use in combination with accupril unless under doctor’s advice.

Pregnant and Nursing mothers

Like all ACE inhibitors, Accupril when used in pregnancy can cause injury and even death to the unborn child during the second and third trimesters. Furthermore, accupril does appear in breast milk and could affect a nursing infant. It is therefore not recommended to be taking in either case.

Storage

Accupril should be stored at room temperature away from intense light.

Accupril notes

Known by the product name Accupro and having the generic name Quinapril, accupril is a medication that is used to treat high blood pressure and is taken alone or in combination with a water[-contol] pill containing thiazide like HydroDIURIL. Belonging to the family of drugs called "ACE inhibitors”, accupril medication helps in preventing a blood-chemical called angiotensin I from being converted to a more potent form that causes an increase in salt and water retention in your body. accupril drug [Accupril] is also found to enhance the flow of blood throughout your blood vessels. Accupril in combination with other drugs is also prescribed for curing congestive heart failure.

Before taking accupril, it is important that you are aware of all the necessary accupril prescription information and accupril mg dosage instructions so as to prevent over-dosage and consequent after-effects. Taking Accupril regularly is highly beneficial as it helps in reducing blood pressure; blood pressure declines slowly, though, it may take several weeks to show results. You should also continue taking the drug even after your blood pressure has reduced to a sustained normal level as accupril does not treat the underlying condition, but simply keeps the blood pressure under control.

However, certain side-effects of taking accupril can develop in some patients. Some common accupril side-effects include headache and dizziness and sometimes mild abdominal pain, fatigue, coughing, vomiting, nausea, etc. Some rare cases may occur of angina or chest pain, back pain, stomach or intestine bleeding, constipation, diarrhea, heart rhythm changes, high or low blood pressure, gas, swelling, fluid accumulation, hair loss, hepatitis, heart failure, indigestion, pancreatic inflammation, sweating, sinus inflammation, muscle pain, rashes, palpitations, allergies, sleepiness, infection of urinary tract, vertigo, mouth and throat swelling, skin peeling, kidney failure, itching, insomnia, impotence, high potassium, etc.


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