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Acyclovir prescribing information

 



Acyclovir notes:

Acyclovir that is prescribed along with 5 % Zovirax cream is an oral medication that is highly effective in treating herpes infection starting from the very initial to severe genital herpes infections. zovirax acyclovir helps in reducing the pain and lesions formed from the initial case, while decreasing the severity and frequency in developing persistent infections.

The acyclovir effects benefits for herpes patients in reducing the healing time and preventing the spread of virus and the development of new lesions. Acyclovir also helps in treating chicken pox by cutting down the healing time and curing the lesions along with fever if used within the first 24 hours after the disease is diagnosed. Application of Zovirax ointment helps in treating initial genital herpes, thereby reducing pain, healing time, and spread of the infection.

From 2 g to 800 mg, the dosage of taking Acyclovir defers in people to people and it is important to follow the prescription and Acyclovir mg while taking the medication to avoid over dosage. People with kidney dysfunction are required to take only mild doses of Acyclovir as it can worsen the disease. Always avoid the overuse of Acyclovir and remember to take it only for critical cases of herpes that requires treatment.

Some rare side effects in people using Acyclovir for short term include headache, vomiting, nausea etc. rash and diarrhea are some rare side effects of Acyclovir found in patients treated with Acyclovir for long-term. However, always consult your medical expert before taking the medicine.




Zovirax, Acyclovir

Acyclovir is a synthetic nucleoside analogue drug used to treat various kinds of herpes and this includes cold sore (simplex 1) and genital herpes (simplex 2), vericellar (chicken pox), zoster (shingles) and the Epstein- Barr virus. Acyclovir prevents the replication of the virus by interfering with and capitalising on its replication process.

About the Drug
Herpes is a sexually transmitted disease caused by a virus. The virus replicates by taking over healthy cells and causing it to produce more virus DNA. Acyclovir is activated by the herpes virus which then uses the acyclovir nucleoside instead of the normal cell nucleoside for DNA production. The presence of acyclovir within the structure stops the production of the DNA. As virus infected cells absorb acyclovir more than uninfected cells, further virus replication is prevented and more of the acyclovir is activated hence increasing its anti viral function.

How to Take
Acyclovir can be taken regardless of meal times, it comes in various forms: 400 and 800mg tablets, 200mg capsules, 200mg/5ml suspension, 500 and 1000mg powder for intravenous infusion and as a 5% topical cream or ointment. The oral dosage form can be taken up to 5 times a day for adults and for intravenous delivery 5mg/ml every 8 hours for 7 days is the recommended dosage. Acyclovir can be prescribed for reducing the pain and symptoms of genital herpes and shingles as well as to decreases the recurrence, severity and spread of the infections. It can also help to reduce the healing time, number of lesions and severity of fever when used within 24 hours of the first onset of chicken pox. Intravenous acyclovir is used to treat chicken pox and herpes simples 1 and 2 in patients with compromised immune systems as well as for severe cases of genital herpes. Application of topical herpes can be used to treat the discomforts associated with the early stage of genital herpes, it also decreases the healing time and prevents further spreading of the infection.

Possible Side Effects
Nausea vomiting and Diarrhoea are the more common side effects while less common ones include disorientation, rash, agitation, muscle pain and anaemia. Those especially hypersensitive to acyclovir may experience either of: hepatesis, muscle pain, seizure, anaemia, confusion and agitation.

Drug Interaction
Acyclovir’s activity may be affected by combining it with other drugs. This could cause a decrease or increase in the effectiveness of acyclovir or the other drugs. Levels of phenytoin or valproic acid may be decreased by acyclovir. Probenecid may increase the level of acyclovir in the blood by decreasing the rate at which it is released from the kidney. Acyclovir may increase concentration of theophylline in the blood. Seek medical advice before taking any drugs with acyclovir.

Pregnant and Nursing Mothers
There are insufficient studies on effect of acyclovir on pregnancy however available studies suggest no influence of acyclovir on birth defect. Drug can appear in the breast milk and is therefore not recommended during breastfeeding.

Storage
Store acyclovir at room temperature between 10 and 25 C in a appropriate container.


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