Life-extension drugs

+44 (808) 189 0019
Life-extension drugs
Can not find medication you need on our site? Let us know and we'll supply you any drug you wish!

Alendronate Review Article

 

TextAlendronate belongs to the drug class known as biphosphonates. It slows bone loss and thus, is used for the treatment and prevention of osteoporosis which is also known as ďthe brittle bone diseaseĒ in post-menopausal women. It is also utilized to increase the bone mass of men who are suffering from osteoporosis. It is recommended for both women and men who have acquired a form of osteoporosis which is occasionally due to steroid medications, for instance prednisone. This drug is also used to mitigate pain caused by Pagetís disease of the bone which is a painful condition that deforms and weakens the bones. Alendronate is given daily or weekly. Its side effects may include ulceration of the esophagus, skin rash, and eye problems. Alendronate is a drug classified as biphosphonates that is prescribed in treatment of bone disorders such as osteoporosis. Though it may be sold on its own, Alendronate is commonly marketed along with vitamin D which increases the absorption of the drug as well as helps in strengthening the bones.

Dosage Packing Price Add to basket
70 mg 4 tab USD 47.00 Add to Basket

On clinical trial, Aledronate was compared to Pamidronate which was also under the same class and for the same use on osteoporosis. However, on this study, both drugs were tested for Pagetís disease of the bone which was a chronic condition causing abnormal enlargement and deformation of certain bones. Both of these drugs are considered second and third generation biphosphonates medications for Pagetís disease of the bone and are preferable than the previous drugs calcitonin and etidronate for treatment.

To determine which of these drugs is better, researchers used a 2 year randomized clinical trial for 72 subjects with the bone disease. They were then randomly assigned to either take oral Alendronate, intravenous Pamidronate or placebo. A certain key factor in this study though, was that there was a group which has already been previously treated with Pamidronate alone. The subjects were to receive either Pamidronate in a single infusion or Alendronate in a dosage of 40 mg per day. ALP and urine deoxypyridinoline/ creatinine ratio was monitored to determine for biochemical remission. Over time, they found that both drugs have almost the same level of effectiveness for biochemical remission but Alendronate had more efficacy in achieving this on patients who have been previously treated with the other drug.

References:

1. Peters ML, Leonard M, Licata AA. 2001. Role of Alendronate and Risedronate in Preventing and Treating Osteoporosis. Cleve Clin J Med 68:945-951.

2. Walsh JP, Ward LC, Stewart GO, Will RK, Criddle RA, Prince RL, Stuckey BG, Dhaliwal SS, Bhagat CI, Retallack RW, Kent GN, Drury PJ, Vasikaran S, Gutteridge DH. 2004. A randomized clinical trial comparing oral alendronate and intravenous pamidronate for the treatment of Paget's disease of bone. Bone, 34(4):747-54.


 

My BasketMy Basket

Bone resorption inhibitor
Alendronate
Alendronate Review Article


Buy here


Alendronate prescribing information


Newsletter subscription


Product search

Product list

- ACARBOSE
- ACCUPRIL
- ACIPHEX
- ACTOS
- ACYCLOVIR
- ADALAT
- ADAMANTAN
- AERIUS
- ALENDRONATE
- ALLEGRA
- ALLOPURINOL
- AMANTADINE
- AMARYL
- AMINOGUANIDINE
- AMITRIPTYLINE
- ARAVA
- AREDIA
- ARICEPT
- ARIMIDEX
- ASTRAGALOSIDE IV
- ATORVASTATIN
- AUGMENTIN
- AVAPRO
- AVASTIN
- AVEMAR IMMUNE BOOSTER
- AZARGA
- AZOPT
- B-VITAMIN COMPLEX
- B-VITAMIN COMPLEX FORTE
- B6 VITAMIN
- BENICAR
- BONIVA
- BROMOCRIPTINE
- BURDOCK ROOT OIL
- CAFFEINE COMPLEX
- CALCITRIO
- CAMPTO
- CASODEX
- CAVINTON
- CENTROPHENOXINE
- CIALIS
- CIPROBAY
- CLIMAGEST
- CLOMID
- CLOTRIMAZOLE, BIFONAZOLE
- COAXIL
- COENZYME Q10
- COMBIVIR
- COMPETACT
- COMTAN
- COVEREX
- COVERSYL
- COZAAR
- CRESTOR
- CYCLOASTRAGENOL (TA-65 ACTIVE SUBSTANCE)
- CYMBALTA
- D3 VITAMIN
- DEPAKOTE
- DEPO-MEDROL
- DEPRENYL
- DIABENOL
- DIFLUCAN
- DOXYCYCLINE
- E VITAMIN
- ECHINACEA/ VIT. C 1000/ ZINC
- EFFEXOR
- ELDEPRYL
- EULEXIN
- EVISTA
- EXELON
- FARESTON
- FAT BURNER
- FEMARA
- FISH OIL
- FLOMAX
- FLUCONAZOLE
- FOLIC ACID
- FOSAMAX
- GALVUS
- GLEEVEC, GLIVEC
- GLUCOBAY
- GLUCOBENE
- GLUCONORM
- GLUCOPHAGE, GLUCOPHAGE XR
- IBUPROFEN
- IMATINIB
- IMIGRAN
- IMUNOVIR
- INULIN
- IODIDE (KI)
- IODINE WATER
- IRESSA
- ISOPRINOSINE
- JANUMET
- JANUVIA
- JUMEX
- K-2 VITAMIN
- KALETRA
- LAMISIL
- LESCOL
- LEUZEA ROOT
- LEVAQUIN, LEVOFLOXACIN
- LIFE EXTENDING KIT
- LIPITOR
- LIPOIC ACID
- LOTENSIN
- MACA VIBE
- MADOPAR
- MEGACE
- MELATONIN
- MEMANTINE
- METFORMIN
- METOPROLOL
- MILGAMMA
- MIRAPEXIN
- MOBIC
- MOVALIS
- MUMIJO (MUMIO)
- NADH
- NEUPRO
- NEXIUM
- NIZORAL
- NOLVADEX
- NOOTROPIL
- NOOTROPYL
- NORVASC
- ORUNGAL
- OSELTAMIVIR
- PANTOCRIN
- PIKAMILON (PICAMILON)
- PIRACETAM
- PLAVIX
- PRECOSE
- PROSCAR
- PUMPKINSEED OIL
- RALOXIFENE
- RAPAMYCIN
- RED WINE HIGH IN RESVERATROL
- RESVERATROL
- REVALID CAPSULES
- REVALID CREAM
- REVALID HAIR TONIC
- REVALID SHAMPOO AND CONDITIONER
- REYATAZ
- RHODIOLA ROOT
- RHODIOLA TABLETS
- ROSUVASTATIN
- RUTIN
- SCHISANDRA
- SEA-BUCKTHORN
- SELEGILIN
- SELENIUM
- SEROQUEL
- SINEMET
- SINGULAIR
- SPORANOX
- STABLON
- SUSTIVA
- TAMIFLU
- TAMOXIFEN (ZITAZONIUM)
- TASMAR
- TELFAST
- THIOGAMMA (LIPOIC ACID)
- TOLCAPONE
- TOPAMAX
- TRITICO
- TRUVADA
- VALDOXAN
- VEPESID
- VFEND (VORICONAZOLE)
- VIAGRA
- VINPOCETINE
- VINPOTROPILE
- VIREAD
- XALATAN
- XELODA
- XENICAL
- XYLOMETAZOLINE / OTRIVIN
- ZETIA
- ZIAGEN
- ZINC (ZN)
- ZITHROMAX
- ZOCOR
- ZOFRAN
- ZOVIRAX
- ZYPREXA
- ZYRTEC

You are located on a secure website.
Customer data is for our internal use only and will be treated as confidential.

eXTReMe Tracker