Life-extension drugs

+44 (808) 189 0019
Life-extension drugs
Can not find medication you need on our site? Let us know and we'll supply you any drug you wish!

Allegra Review Article

 

allergyAllegra or Telfast (generic name: fexofenadine) is an antihistamine which is used to reduce the symptoms of hay fever, seasonal allergic rhinitis, and other types of allergies and for the treatment of chronic idiopathic urticaria. Like other antihistamines, this drug prevents the action of histamine on the eyes and nose and it is taken to relieve symptoms of allergies including runny nose, watery and itchy eyes, sneezing, and itchy throat. Since it is not a therapeutic drug, fexofenadine only prevents the aggravation of urticaria and rhinitis but does not really cure it. The usual side effects of the drug include nausea, headache, dizziness, sleepiness, nervousness, and drowsiness. However, since fenoxadine is similar to other antihistamines that belong to the second and third-generation, it does not readily cross the blood-brain barrier and therefore causes less drowsiness than histamine-receptor antagonists that belong to the first generation.

Allegra is a trademark name for Fexofenadine which is an antihistamine drug class prescribed for Hay fever or better known as allergic rhinitis and other allergy attacks. It is considered as a second and third generation group of antihistamine drugs which does not infiltrate the blood-brain barrier in an instant. This effect is avoided so as not to induce drowsiness to the person who had taken the drug. However, it is still effective in preventing allergy symptoms and antagonist to the H1 receptor by blocking it. Allegra should only be used before the attack of allergy to relieve the symptoms but it will not treat Hay Fever or Urticaria itself. Continue reading...

Dosage Packing Price Add to basket
120 mg 10 tab ($0.9 per tab) USD 9.00 Add to Basket
120 mg 30 tab ($0.7 per tab) USD 22.00 Add to Basket
120 mg 90 tab ($0.6 per tab) USD 59.00 Add to Basket
180 mg 10 tab ($1.1 per tab) USD 11.00 Add to Basket
180 mg 30 tab ($1.1 per tab) USD 32.00 Add to Basket
180 mg 90 tab ($1.0 per tab) USD 89.00 Add to Basket

Several randomized clinical trials were created to prove the efficacy and safety of Allegra for seasonal allergic rhinitis. Surprisingly, despite Allegra being commonly prescribed, no concrete evidence has been established yet until this decade where numerous trials were conducted with controlled placebo groups. One study aimed to piece together around 2,150 articles with 20 relevant clinical trials to Allegra and its effects on Allergic Rhinitis patients. It was found that positive results were consistent throughout valid studies which passed on the researchersí inclusion and exclusion criteria. Additionally, it showed immediate improvement both in the adult and pediatric group of participants with allergic rhinitis.

In Asia, there is a prevalent condition called Japanese cedar pollinosis. This condition is very common form of allergy in the country and may lead to serious conditions such as asthma. It is caused by Japanese monkeys which carry the Japanese cedar. Once it has been transmitted to humans, it will cause excessive tear production, eye irritation, sneezing and rhinorrhea. On a clinical trial, Allegra was tested for safety and efficacy on the condition. As an oral H1 antihistamine, it has been a favorable prescription to patients with such condition. The treatment was continued after the 4th and the 7th week of the trial. Nasal symptoms through report and observation, activity impairment and attention or sleepiness using the digit cancellation test were taken note of during the trial visits. No adverse effects were reported and symptom relief was reported after 2 to 4 hours.
To further prove the safety of the drug fexofenadine, a research aimed to determine the link between plasma concentration and QTc interval of the heart when it is being used. The results showed that the peak concentration time of fexofenadine did not meet the cardiac maximum effect as proven by the QTc interval. This ultimately meant that fexofenadine had no negative effects on the cardiac condition of the person.

References:

1. Compalati E, Baena-Cagnani R, Penagos M, Badellino H, Braido F, G?mez RM, Canonica GW, Baena-Cagnani CE. 2011. Systematic Review on the Efficacy of Fexofenadine in Seasonal Allergic Rhinitis: A Meta-Analysis of Randomized, Double-Blind, Placebo-Controlled Clinical Trials. Int Arch Allergy Immunol, 156(1):1-15.

2. Enomoto T, Lu HQ, Yin M, Sakoda T, Dake Y, Enomoto K, Ide T, Cheng L. 2009. Evaluation of the efficacy and safety of olopatadine and fexofenadine compared with placebo in Japanese cedar pollinosis using an environmental exposure unit. J Investig Allergol Clin Immunol. 19(4):299-305.

3. Vyas FI, Prakash S, Singh AJ. 2010. QTc interval prolongation by fexofenadine in healthy human volunteers and its correlation with plasma levels of fexofenadine: A demonstration of anticlockwise hysteresis. Indian J Pharmacol. 42(6):366-9.


 

My BasketMy Basket

Allergy
Allegra
Allegra Review Article


Buy here


Allegra prescribing information


Newsletter subscription


Product search

Product list

- ACARBOSE
- ACCUPRIL
- ACIPHEX
- ACTOS
- ACYCLOVIR
- ADALAT
- ADAMANTAN
- AERIUS
- ALENDRONATE
- ALLEGRA
- ALLOPURINOL
- AMANTADINE
- AMARYL
- AMINOGUANIDINE
- AMITRIPTYLINE
- ARAVA
- AREDIA
- ARICEPT
- ARIMIDEX
- ASTRAGALOSIDE IV
- ATORVASTATIN
- AUGMENTIN
- AVAPRO
- AVASTIN
- AVEMAR IMMUNE BOOSTER
- AZARGA
- AZOPT
- B-VITAMIN COMPLEX
- B-VITAMIN COMPLEX FORTE
- B6 VITAMIN
- BENICAR
- BONIVA
- BROMOCRIPTINE
- BURDOCK ROOT OIL
- CAFFEINE COMPLEX
- CALCITRIO
- CAMPTO
- CASODEX
- CAVINTON
- CENTROPHENOXINE
- CIALIS
- CIPROBAY
- CLIMAGEST
- CLOMID
- CLOTRIMAZOLE, BIFONAZOLE
- COAXIL
- COENZYME Q10
- COMBIVIR
- COMPETACT
- COMTAN
- COVEREX
- COVERSYL
- COZAAR
- CRESTOR
- CYCLOASTRAGENOL (TA-65 ACTIVE SUBSTANCE)
- CYMBALTA
- D3 VITAMIN
- DEPAKOTE
- DEPO-MEDROL
- DEPRENYL
- DIABENOL
- DIFLUCAN
- DOXYCYCLINE
- E VITAMIN
- ECHINACEA/ VIT. C 1000/ ZINC
- EFFEXOR
- ELDEPRYL
- EULEXIN
- EVISTA
- EXELON
- FARESTON
- FAT BURNER
- FEMARA
- FISH OIL
- FLOMAX
- FLUCONAZOLE
- FOLIC ACID
- FOSAMAX
- GALVUS
- GLEEVEC, GLIVEC
- GLUCOBAY
- GLUCOBENE
- GLUCONORM
- GLUCOPHAGE, GLUCOPHAGE XR
- IBUPROFEN
- IMATINIB
- IMIGRAN
- IMUNOVIR
- INULIN
- IODIDE (KI)
- IODINE WATER
- IRESSA
- ISOPRINOSINE
- JANUMET
- JANUVIA
- JUMEX
- K-2 VITAMIN
- KALETRA
- LAMISIL
- LESCOL
- LEUZEA ROOT
- LEVAQUIN, LEVOFLOXACIN
- LIFE EXTENDING KIT
- LIPITOR
- LIPOIC ACID
- LOTENSIN
- MACA VIBE
- MADOPAR
- MEGACE
- MELATONIN
- MEMANTINE
- METFORMIN
- METOPROLOL
- MILGAMMA
- MIRAPEXIN
- MOBIC
- MOVALIS
- MUMIJO (MUMIO)
- NADH
- NEUPRO
- NEXIUM
- NIZORAL
- NOLVADEX
- NOOTROPIL
- NOOTROPYL
- NORVASC
- ORUNGAL
- OSELTAMIVIR
- PANTOCRIN
- PIKAMILON (PICAMILON)
- PIRACETAM
- PLAVIX
- PRECOSE
- PROSCAR
- PUMPKINSEED OIL
- RALOXIFENE
- RAPAMYCIN
- RED WINE HIGH IN RESVERATROL
- RESVERATROL
- REVALID CAPSULES
- REVALID CREAM
- REVALID HAIR TONIC
- REVALID SHAMPOO AND CONDITIONER
- REYATAZ
- RHODIOLA ROOT
- RHODIOLA TABLETS
- ROSUVASTATIN
- RUTIN
- SCHISANDRA
- SEA-BUCKTHORN
- SELEGILIN
- SELENIUM
- SEROQUEL
- SINEMET
- SINGULAIR
- SPORANOX
- STABLON
- SUSTIVA
- TAMIFLU
- TAMOXIFEN (ZITAZONIUM)
- TASMAR
- TELFAST
- THIOGAMMA (LIPOIC ACID)
- TOLCAPONE
- TOPAMAX
- TRITICO
- TRUVADA
- VALDOXAN
- VEPESID
- VFEND (VORICONAZOLE)
- VIAGRA
- VINPOCETINE
- VINPOTROPILE
- VIREAD
- XALATAN
- XELODA
- XENICAL
- XYLOMETAZOLINE / OTRIVIN
- ZETIA
- ZIAGEN
- ZINC (ZN)
- ZITHROMAX
- ZOCOR
- ZOFRAN
- ZOVIRAX
- ZYPREXA
- ZYRTEC

You are located on a secure website.
Customer data is for our internal use only and will be treated as confidential.

eXTReMe Tracker