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Azarga Review Article

 

azagraAzarga has two active substances: Timolol and Brinzolamide. It is an eye-drop suspension that is utilized to decrease ocular-pressure or IOP which refers to pressure inside the eye. It is prescribed to adults who are suffering from open-angle glaucoma which is an illness wherein the pressure in the eye is raised since the fluid cannot be drained out of the eye. It is also recommended for adults who have eye-pressure that is elevated or higher than normal, also known as ocular hypertension. Azarga is utilized when treatment with a medication that contains only one active substance has been carried out but failed to reduce the IOP adequately. Common side effects include blurred vision, dysgeusia, eye irritation, sensation of a foreign body in the eye, and eye pain.

Azarga is an eye drop for treating condition whereby the pressure in the eye is increased beyond the normal eye pressure. It consists of two active ingredients which are Timolol and Brinzolamide and it is used where eye medications consisting of a single active ingredient have proved ineffective or inappropriate for a patient. Such rise in ocular pressure could be as a result of conditions such as open-angle glaucoma due to fluid retention in the eye when the fluid draining mechanism of the eye malfunctions or for those with ocular hypertension. Azarga has been clinically tested on humans as an effective way to relieve increased intraocular pressure. Continue reading...

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About Azarga

Increased pressure in the eye may be due to an increased production of bicarbonate ions which are essential in the production of the aqueous humor (fluid in the eyes). The bicarbonate ions are produced by an enzyme called carbonic anhydrase. If not treated, this increased ocular pressure may lead to serious damage to the sensitive parts of the eye especially the retina; the back of the eye sensitive to light, and the optic nerve which connects the eye with the brain. Azarga helps to decrease this pressure by blocking the action of this enzyme. With the combination of Brinzolamide; which blocks the carbonic anhydrase enzyme and Timolol a beta blocker widely used in the treatment of glaucoma for over three decades; Azarga provides a more effective treatment for glaucoma and ocular hypertension or similar eye conditions.


How to Take Azarga

The drug is available in the form of an eye drop suspension which is to be shaken well before use for even distribution of the formulation. The usual recommended usage is one drop twice daily on the eye thatís affected. Vision could be temporarily blurred while taking Azarga and this may limit the individualís ability to perform task such as driving and operation of machinery. However this blurred vision is only temporary and once cleared the person can continue with these activities.


Contraindications

Any patient that may be allergic to the active ingredients or any of the other ingredients in the drug should not use Azarga. It is also not recommended for patients who have suffered from asthma, sever pulmonary and cardiovascular diseases, severe nose or airways allergy, hyperchloraemic acidosis and sever kidney problems. Furthermore, patients wearing contact lenses should beware of discoloring of t contact lenses by the drug.


Possible Side Effects

The possible side effect which have been reported in some patients during clinical tests include: Blurred vision, pain in the eyes and sensation of substances being present in the eye, dysgeusia (taste of bitterness or unusual taste in the mouth) and eye irritation.


Pregnant and Nursing mother

Medications taken during whole pregnancy or certain periods of pregnancy may have damaging effect on the unborn child therefore pregnant mothers should contact their healthcare provider before taking any medication. Likewise since certain drugs taken by the mother can get into the breast milk outing the child at great risk, it is essential to abstain from certain drugs while breastfeeding. If it is important to the motherís health medical consultation must be sought to discuss best measure.


 

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