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B-vitamin complex Review Article

 

B vitamin complexB-vitamins belong to the group of vitamins that are soluble in water and play crucial roles in the process of cell metabolism. In the past, it was believed that B-vitamins are a single vitamin similar to Vitamin A, Vitamin C, etc. and was called Vitamin B. It was later discovered that B-vitamins are chemically diverse vitamins that are usually present in the same foods (usually, whole unprocessed foods). Thus, a supplement that contains all the eight B-vitamins is referred to as B-vitamin complex. B-vitamins are essential in supporting and increasing metabolic rate, maintaining healthy muscle tone and skin, enhancing immunity and functions of the nervous system, promoting cell growth and cell division, and reducing the risk of having pancreatic cancer.
The B vitamins are a group of water-soluble vitamins that play important roles in cell metabolism. The B vitamins were once thought to be a single vitamin, referred to as vitamin B (much as people refer to vitamin C or vitamin D). Later research showed that they are chemically distinct vitamins that often coexist in the same foods. In general, supplements containing all eight are referred to as a vitamin B complex. Individual B vitamin supplements are referred to by the specific name of each vitamin (e.g., B1, B2, B3 etc.).
EACH TABLET CONTAINS:
B1-10 mg, B2-10 mg, B6-10 mg, B12-10 mcg, Biotin 0.5 mg, Niacin-50 mg, Pantothenic acid-35 mg, Vitamin C - 500 mg, Zink-7.5 mg.
More about Zinc (Zn) read our article. Continue reading...

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Health benefits B vitamins is necessary in order to:

Support and increase the rate of metabolism
Maintain healthy skin and muscle tone
Enhance immune and nervous system function
Promote cell growth and division, including that of the red blood cells that help prevent anemia
Reduce the risk of pancreatic cancer - one of the most lethal forms of cancer[1] - when consumed in food, but not when ingested in vitamin tablet form.
All B vitamins are water-soluble, and are dispersed throughout the body. Most of the B vitamins must be replenished regularly, since any excess is excreted in the urine.

A 2010 study concluded that taking vitamins B9, B6 and B12 may slow brain atrophy in patients with mild cognitive impairment.[5] Such atrophy is one predictor of conversion from MCI to Alzheimer's disease. However, the study was conducted by a former collaborator of Patrick Holford, a controversial figure who promotes vitamins as cures for ailments ranging from HIV to autism, and the result has been criticized by Carl Heneghan, Director of the Centre for Evidence Based Medicine and clinical lecturer at the University of Oxford, for excluding the one third of initial participants who dropped out or were not followed up, and for quoting a "30% reduction in rate of decline" which translates to only a 0.3% absolute change.

B vitamin deficiencySeveral named vitamin deficiency diseases may result from the lack of sufficient B-vitamins. Deficiencies of other B vitamins result in symptoms that are not part of a named deficiency disease.

List of B vitamins
Vitamin B1 (thiamine)
Vitamin B2 (riboflavin)
Vitamin B3 (niacin or niacinamide)
Vitamin B5 (pantothenic acid)
Vitamin B6 (pyridoxine, pyridoxal, or pyridoxamine, or pyridoxine hydrochloride)
Vitamin B7 (biotin)
Vitamin B9 (folic acid)
Vitamin B12 (various cobalamins; commonly cyanocobalamin in vitamin supplements).

Vitamin Name Deficiency effects:

Vitamin B1
thiamine Deficiency causes beriberi. Symptoms of this disease of the nervous system include weight loss, emotional disturbances, Wernicke's encephalopathy (impaired sensory perception), weakness and pain in the limbs, periods of irregular heartbeat, and edema (swelling of bodily tissues). Heart failure and death may occur in advanced cases. Chronic thiamine deficiency can also cause Korsakoff's syndrome, an irreversible psychosis characterized by amnesia and confabulation.

Vitamin B2
riboflavin Deficiency causes ariboflavinosis. Symptoms may include cheilosis (cracks in the lips), high sensitivity to sunlight, angular cheilitis, glossitis (inflammation of the tongue), seborrheic dermatitis or pseudo-syphilis (particularly affecting the scrotum or labia majora and the mouth), pharyngitis (sore throat), hyperemia, and edema of the pharyngeal and oral mucosa.
Vitamin B3 niacin Deficiency, along with a deficiency of tryptophan causes pellagra. Symptoms include aggression, dermatitis, insomnia, weakness, mental confusion, and diarrhea. In advanced cases, pellagra may lead to dementia and death (the 3(+1) Ds: dermatitis, diarrhea, dementia, and death).

Vitamin B5
pantothenic acid Deficiency can result in acne and paresthesia, although it is uncommon.

Vitamin B6
pyridoxine Deficiency may lead to microcytic anemia (because pyridoxyl phosphate is the cofactor for heme synthesis), depression, dermatitis, high blood pressure (hypertension), water retention, and elevated levels of homocysteine.

Vitamin B7
biotin Deficiency does not typically cause symptoms in adults but may lead to impaired growth and neurological disorders in infants. Multiple carboxylase deficiency, an inborn error of metabolism, can lead to biotin deficiency even when dietary biotin intake is normal.
Vitamin B9 folic acid Deficiency results in a macrocytic anemia, and elevated levels of homocysteine. Deficiency in pregnant women can lead to birth defects. Supplementation is often recommended during pregnancy. Researchers have shown that folic acid might also slow the insidious effects of age on the brain.

Vitamin B12
cobalamin Deficiency results in a macrocytic anemia, elevated homocysteine, peripheral neuropathy, memory loss and other cognitive deficits. It is most likely to occur among elderly people, as absorption through the gut declines with age; the autoimmune disease pernicious anemia is another common cause. It can also cause symptoms of mania and psychosis. In rare extreme cases, paralysis can result.


 

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