Life-extension drugs

Life-extension drugs



 flavonoids in aronia Flavonoids are anti-inflammatory agents - do great benefit in cancer and cardiovascular disease. Inflamation: Inflammation is an orchestrated biological process, induced by microbial infection or tissue injury. A major trigger of inflammation is the recognition of microbes by specific receptors of the innate immune system, which play a crucial role in the induction of early signals initiating and establishing the inflammatory setting. A main function of inflammation is to resolve infection and to repair the damage in order to achieve homeostasis equilibrium. Thus, the ideal inflammatory response is rapid and destructive, yet specific and self-limiting. The importance of this balance is demonstrated by findings in certain chronic infectious or inflammatory disorders, that the inflammatory response causes more damage to the host than the microbe. Inflammation and the immune system are intimately tied. Indeed, an over activation of innate immune response can cause chronic infection or chronic inflammation due to an inefficient regulation or resolution of the inflammatory response.
 flavonoids in grapefruit Bioflavonoids, found in plants and food are very important anti-aging substances. Apigenin and Luteolin: These flavonoids found in such foods as parsley, artichoke, basil, and celery, spinach. Both compounds have shown the ability to protect cells against cancer and also to inhibit DNA oxidative damage. In a study on antioxidant potency, apigenin proved more effective than vitamin C in reducing oxidative damage to DNA. When measured against 27 citrus flavonoids, luteolin had the most antiproliferative activities against tumors. Naringin - gives a bitter taste in grapefruits. Morin - reach in guava Rutin - most potent flavonoid, inhibitor of VEGF release.

Products: Flavonoids

Red Wine high in Resveratrol
Hungarian red wine Pinot Noir has one of the highest content of Resveratrol, Quercetin and Anthocianins. The highest polyphenol content and antioxidant activity was in Pinot Noir and in Merlot from Villany.
See also: General premature aging.

Resveratrol is a naturally occurring phytoalexin produced naturally by several plants due to bacteria and fungi. The effect of resveratrol on life span of fruit flies and nematode worms is still under debate. During mouse and rat experiments some beneficial cardiovascular effects of resveratrol have been reported, such as: anti-inflammatory, anti-cancer and blood-sugar-lowering. Resveratrol is a constituent of red wine and it can be also found in the skin of red grapes. Furthermore, Resveratrol anti-inflammatory effect have been demonstrated during several animal studies.

Rutin is a citrus flavonoid glycoside found in buckwheat, the leaves and petioles of Rheum species, and asparagus. Rutin is also found in the fruit of the Fava D'Anta tree (from Brazil), fruits and fruit rinds (especially citrus fruits (orange, grapefruit, lemon, lime)) and berries such as mulberry and cranberries. Rutinin the form of ferulic acid, can reduce the cytotoxicity of oxidized LDL cholesterol and lower the risk of heart disease. There are also reports available that rutin can be use for the treatment of hemorrhoids, varicosis, and microangiopathy. Rutin is the glycoside between the flavonol quercetin and the disaccharide rutinose.


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