Clomid Clomid (Clomifene, Clomiphene, Serophene, Milophene) refers to a group of medicines called anti-estrogens. Drugs in this group specifically bind to estrogen receptors in the hypothalamus and the ovaries. In small doses, the drug enhances the secretion of gonadotropins and stimulates ovulation. At a low content of endogenous estrogens in the body, these drug has a mild estrogenic effect, but at high levels of estrogen, it has an antiestrogenic effect. In large doses this drug can inhibit the secretion of gonadotropins. In connection with abovementioned properties in appropriate doses Clomid is used as a means of stimulating ovulation in anovulatory ovarian dysfunction and associated with it infertility in women. It is also applied for treatment of breast cancer. Due to the fact that Clomid is able of stimulation of gonadotropin secretion the drug is also used for treatment of androgen deficiency, oligospermia in men and delay of sexual and physical development of adolescent males.