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Scientists hope to discover the Mechanism of action of Ultraviolet light to chronic autoimmune skin disease

Scientists hope to discover the Mechanism of action of Ultraviolet light to chronic autoimmune skin disease

Sunshine and ultraviolet light commonly used for treatment for psoriasis and shows good results. But still difficult to explain this light’s therapeutic effects.
A new clinical trial started in the Center for Clinical and Translational Science in The Rockefeller University Hospital. 20 patients will visit the hospital three times a week for up to four months to receive narrowband ultraviolet light B (UVB) treatment. Patients will give skin and blood samples as the treatment takes its course, giving the scientists the possibility to study what is happening at the molecular level as the skin gets better. Patients receive the treatment, brief blasts of UVB, standing inside an upright cabinet whose inside is lined with fluorescent tube lights. The duration of the light exposure increases over the course of the treatment.
Scientists hope to have some preliminary results in about a year. “We are excited about studying this commonly used therapy for psoriasis with modern methods, and hope that this will lead to a better understanding of this complicated and common skin disease,” she says.

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