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Nexium Review Article

 

Nexium is basically used for the treatment of symptomatic resolution of diagnostically confirmed erosive esophagitis. It reduces the gastric ulcers associated with the continuous NSAID therapy in patients at risk for developing gastric ulcers. This medication along with amoxicillin and clarithromycin is used for the treatment of patients with H.pylori infection and duodenal ulcer disease. Patient should not take this medication if allergic to esomeprazole or any other benzimidazole medication. Nexium is not use for immediate relief of heartburn symptoms. It is given for 4 to 8 weeks only as per the physician’s direction.

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Nexium generic (generic - what is it?)

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Indications:
Nexium decreases the amount of acid produced in the stomach.
Nexium is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. It is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).

Nexium may also be given to prevent gastric ulcer caused by infection with helicobacter pylori (H. pylori), or by the use of nonsteroidal anti-inflammatory drugs (NSAIDs).

Nexium may also be used for purposes other than those listed in this medication guide.

Important information about Nexium
Do not use Nexium if you are allergic to esomeprazole or to any other benzimidazole medication such as albendazole (Albenza), or mebendazole (Vermox). Before taking Nexium, tell your doctor if you have ever had liver disease or any type of heart disease. You may need a dose adjustment or special tests during treatment.

Some conditions are treated with a combination of Nexium and antibiotics. To best treat your condition, use all of your medications as directed by your doctor. Be sure to read the medication guide or patient instructions provided with each of your medications. Do not change your doses or medication schedule without advice from your doctor.

Take Nexium for the entire length of time prescribed by your doctor. Your symptoms may get better before your treatment is completed. Do not crush, break, or open a delayed-release capsule. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or opening the pill would cause too much of the drug to be released at one time.

Before taking Nexium
Do not use Nexium if you are allergic to esomeprazole or to any other benzimidazole medication such as albendazole (Albenza), or mebendazole (Vermox). Before taking Nexium, tell your doctor if you have ever had liver disease or any type of heart disease. You may need a dose adjustment or special tests during treatment.

Some conditions are treated with a combination of Nexium and antibiotics. To best treat your condition, use all of your medications as directed by your doctor. Be sure to read the medication guide or patient instructions provided with each of your medications. Do not change your doses or medication schedule without advice from your doctor.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether Nexium passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Nexium?
Take Nexium exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
This medicine is usually given for 4 to 8 weeks only. Your doctor may recommend a second course of treatment if you need additional healing time. Take each dose with a full glass (8 ounces) of water. Nexium should be taken at least one hour before a meal. Do not crush, break, or open a delayed-release capsule. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or opening the pill would cause too much of the drug to be released at one time.

You may open the delayed-release capsule and sprinkle the medicine into a spoonful of pudding or applesauce to make swallowing easier. Swallow this mixture right away without chewing. Do not save the mixture for later use. Discard the empty capsule.

Nexium can be given through a nasogastric (NG) feeding tube. Open the capsule and sprinkle the medicine into a 60-milliliter syringe. Mix in 50 milliliters of water. Place the plunger into the syringe and shake the mixture well. Make sure there are no medicine granules stuck in the tip of the syringe. Attach the syringe to the NG tube and push the plunger down to empty the syringe into the tube. Then flush the tube with more water to wash the contents down.

It is important to use Nexium regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before your treatment is completed. Store Nexium at room temperature away from moisture and heat.

What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an Nexium overdose include confusion, headache, drowsiness, blurred vision, fast heartbeat, nausea, dry mouth, sweating, flushing, shortness of breath, tremor, loss of coordination, or seizure (convulsions).

What should I avoid while taking Nexium?
Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are using Nexium.

Nexium side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Other less serious Nexium side effects are more likely to occur, such as:
headache;
diarrhea;
nausea, stomach pain, gas, constipation; or
dry mouth.

What other drugs will affect Nexium?
Before taking Nexium, tell your doctor if you are using any of the following drugs:
clopidogrel (Plavix);
digoxin (Lanoxin, Lanoxicaps);
diazepam (Valium);
ketoconazole (Nizoral);
HIV or AIDS medication such as atazanavir (Reyataz), nelfinavir (Viracept), saquinavir (Invirase), and others;
iron (Feosol, Mol-Iron, Fergon, Femiron, others); or
a blood thinner such as warfarin (Coumadin).

If you are using any of these drugs, you may not be able to use Nexium, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect Nexium. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Nexium 20 mg - opaque, hard-gelatin, amethyst-colored capsules with two yellow bars on the cap

Nexium 40 mg - opaque, hard-gelatin, amethyst-colored capsules with three yellow bars on the cap


Nexium notes:

Nexium’s generic name is esomeprazole. Nexium (Esomeprazole) is used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastro esophageal reflux disease (GORD/GERD) and Zollinger-Ellison syndrome.

Nexium esomeprazole is a proton pump inhibitor (PPI), It helps in blocking the production of acid by the stomach. Nexium (Esomeprazole) is used to treat symptoms of gastro esophageal reflux disease (GERD) and other conditions involving excessive stomach acid. Nexium esomeprazole is used for the patients having the history of irritation and swelling of the Esophagus when drug cannot be consumed by mouth.

Nexiam is a common misspelling of Nexium. Nexiam is a brand name of Nexium in Belgium.

Esomeprazole tablets are used in the treatment of gastro esophageal reflux disease, a condition that involves the backward flow of acid from the stomach causing heartburn and injury to the esophagus.

Nexium side effects includes difficulty in breathing; swelling of face, lips, tongue and throat, chest pain or tightness, dark yellow or brown urine, shortness of breath, skin rash, unusual tiredness or fatigue.


Super gene discovered to fight against aging – says Scientists

In the recent developments to find anti aging pill, scientists have announced that they have achieve a break through toward this direction by discovering three super genes that are related to increased longevity and decreased risk of feebleness by impacting on insulin signalling. Researchers think that reducing sugar intake in diet is the primary step against aging. They are planning to produce drug which can mimic the benefits of genes.

Dr. Nir Barzilai, the lead scientist said that the plan is to produce drug which can mimic the benefits of genes and if they get success in achieving this, than people can look for a terrific long life. Carriers of the genes have 1 in 500 chances of making it to 100 which is significantly higher than the odds of non carriers; currently 1 in 10,000 they have reduced ability for developing high cholesterol and diabetes.

Based on this recent research, the increased longevity and resistance to diseases can be explained fully by gene conferring improved insulin sensitivity upon the carrier. The reduced insulin shows increase in systemic inflammation, mismanagement of lipids, increase risk of cancer and disease such as Alzheimer’s. Scientists strongly believe that this finding is a huge opportunity as the aging population is growing anyway. This would help people to work longer and can have healthier life.


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